Professional Quality Probiotics by Prescript-Assist








Like most practitioners, you know that probiotics are an essential part of your patients' gastrointestinal health...


But probiotic supplements come with a problem that sets them apart from every other supplement you recommend:


Probiotics will have limited effect if they're not alive.


The probiotic supplements you provide your patients must remain viable on the shelf and through the harsh acidic environment of the stomach — delivering active, therapeutic levels at the time they reach the lower GI tract.


This is the Probiotic Viability Puzzle.


A Fundamental Solution: Prescript-Assist™


The logic of Occam's Razor dictates that the simpler a solution to a dilemma, the more truth there is to that solution. Prescript-Assist is the fundamental answer to the probiotic problem.


Other probiotics use high-tech, novel, and unproven manufacturing techniques to force weak, sensitive bacteria through the hostile acidic environment of the early GI tract.


Prescript-Asisst's 29 strains of beneficial microflora are naturally adapted to the GI tract, and inherently resistant to stomach acid and heat.


Finally it's possible to recommend a probiotic that your patients will use, because they know it will work.


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Addressing Patient Compliance


Until recently, probiotics have offered the promise of better GI health but stopped short of offering a practical solution. Products on the market have suffered from a tradeoff between efficacy and convenience, not to mention patient compliance.

“Products on the market have suffered from a tradeoff between efficacy and convenience, not to mention patient compliance.”

The complexity of probiotic choices is increasing — and your patients have a lot of questions:

  • Do my probiotics need to be refrigerated?

  • Will there be enough live organisms in my probiotic to make a difference?

  • Which, if any, of these newfangled probiotic delivery technologies actually work?

  • Can things like nano-encapsulation be dangerous? Are they healthy?

How can you eliminate your patient's concern while also providing them with a trustworthy solution?

Prescript-Assist is the professional-grade probiotic supplement that addresses these problems.


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Introducing Inherent Viability


It's time to stop trying to fit a square peg into a round hole. It's time for something we call Inherent Viability.


To ensure potency and viability of fragile lactic-acid bacteria, refrigeration and a short shelf life are required, reducing convenience and compliance. But manufacturers' attempts to resolve this dilemma have increased consumer doubt and confusion.


Stronger, Innately Resilient Strains

As we see it, the answer to the problem of organism viability is not found in micro-encapsulation or patented enteric coatings. These attempts simply try to force a square peg into a round hole. What's needed is a simple solution that works with bacterial strains' natural adaptive capabilities. Prescript-Assist offers that solution.


Unlike conventional Lactobacillus and Bifidobacterium probiotics, the strains in Prescript-Assist are a balanced formulation of a new generation of probiotics, capable of forming a protective shield until reaching the probiotic-friendly environment of the intestines. Acid, bile and heat-resistant, routine testing of Prescript-Assist confirms > 95% viability two years after date of manufacture.


Supported by peer-reviewed, double-blind, placebo controlled human trial, as well as a one year study verifying long-term efficacy, Prescript-Assist breaks down the barriers to effective use — uniting efficacy, confidence and convenience.


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Five Problems Plaguing Most Probiotics


There are five major problems plaguing other probiotics, solved by Prescript-Assist's multi-strain professional-grade complex:








29 Symbiotic Species Found in Organic, Fertile Tilth


In much the same way that an infant's exposure to maternal bacterial cultures during natural birth help the infant to form a healthy, disease-resistant bacterial defense, environmental and soil-based bacteria commonly found in foods grown in fertile organic tilth assist in growing and maintaining a healthy makeup of internal flora.


This is the basis of SBO (soil-based organisms) probiotics like Prescript-Assist.™ SBO probiotics have risen in recognition recently as clinical evidence grows to support its traditonally-derived approach. Species from the Bacillus genus, a gut-adapted spore-forming bacteria found in Prescript-Assist, have been demonstrated safe and effective in in vitro and in vivo studies.1,2


Dr. Mehmet Oz of the well-known Dr. Oz Show has said, "Spore form probiotics are the Chuck Norris of probiotics: total tough guys. They have to be to survive splashing around in your stomach's acid bath. Wimpier types — including live cultures in yogurt — often throw in the towel."3


Among brands of SBO probiotics, Prescript-Assist offers the greatest diversity of species. It is both the diversity and the resilience of the Prescript-Assist formulation that accounts for its proven success in peer-reviewed, published clinical trials.


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The Importance of Broad Spectrum Diversity


As a result of the Human Microbiome Project — 5 years of NIH-funded research by a consortium of nearly 80 universities and institutions — we now know that number of microbial species found in the human intestines numbers in the thousands rather than hundreds. 4


Perhaps even more importantly, it is understood that the distribution of a variety of strains capable of performing similar tasks is more important than the individual species themselves.5


“We are superorganisms composed of an amalgam of both microbial and H. sapiens cells, where the survival of microbe and human is interdependent.”

— Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine, Cell. Volume 124, Issue 4.

This newfound information shows us that broad spectrum diversity is crucial, and underlines the importance of multi-strain probiotic complexes such as Prescript-Assist.


A review in the scientific journal Cell refers to the gut as a "natural laboratory for studying the 'microevolution' of humans." The authors write: "In this view, we are seen as superorganisms composed of an amalgam of both microbial and H. sapiens cells, where the survival of microbe and human is interdependent."6


With its balanced formulation of 29 beneficial strains selected to mimic the natural flora found in traditional and paleolithic diets, Prescript-Assist is the only professional-grade probiotic to contain 29 species, 12 different genera and all four of the most common phyla found in the human digestive tract, including Firmicutes, Bacteroidetes, Actinobacteria and Proteobacteria.4


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How do you solve the probiotic viability puzzle?


To ensure your patients receive the benefit of viable, effective probiotic delivery, you may have gone to great lengths —

Have you tried any of the following?


  • Educating your patients to store probiotics refrigerated

  • Investigating protective coatings and manufacturing processes that attempt to protect fragile species in transit

  • Seeking out suppliers that ensure refrigeration from manufacture to purchase

  • Even maintaining your own refrigerated storage at your expense

Fortunately, there is an easier, more reliable way to unite convenience, compliance and efficacy. It's based on a fundamental fact of probiotic clinical practice:


The most successful probiotic recommendations control for the most important variable: Strain Viability.

Yesterday's probiotic solutions are anything but conducive to patient confidence. Consumers are aware more and more that lactic-acid based probiotics may or may not contain adequate live organisms. Requiring your patients and all members of the supply chain to maintain uninterrupted product refrigeration is no solution.


Prescript-Assist™ professional broad spectrum probiotic complex puts control back in your hands.


A multi-strain probiotic and prebiotic, supported by peer-reviewed clinical studies, and inherently acid-resistant and shelf-stable without refrigeration, Prescript-Assist stands in a class above all other probiotic solutions.



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References

1. Hong HA, Huang JM, Khaneja R, Hiep LV, Urdaci MC, Cutting SM. The safety of Bacillus subtilis and Bacillus indicus as food probiotics. Journal of Applied Microbiology [Internet]. 2008 Aug [cited 2013 March 14];105(2):510-20. Link


2. Sorokulova IB, Pinchuk IV, Denayrolles M, Osipova IG, Huang JM, Cutting SM, Urdaci MC. The safety of two Bacillus probiotic strains for human use. Digestive Diseases and Sciences [Internet]. 2008 Apr [cited 2013 March 14];53(4):954-63. Link


3. Oz, M, Roizen, M. Cleveland.com [Internet]. Cleveland, Ohio: Cleveland Live LLC. Spore form probiotics keep your digestive tract happy; 2011 October 18 [cited 2013 March 1]. Link


4. Pennisi E. Body's hardworking microbes get some overdue respect. Science. 2010;330(6011):1619.


5. NIH News & Events [Internet]. Bethesda, Maryland: National Institutes of Health. NIH Human Microbiome Project defines normal bacterial makeup of the body; 2012 June 13 [cited 2013 March 1]. Link


6. Ley, R. E., Peterson, D. A. & Gordon, J. I. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell [Internet]. 2006 February 24 [cited 2013 March 1];124(4): 837–848. Link